Table 2. Comparisons of Volume Obtained from NeuroQuant® and Inbrain® in All Subjects and Each Subgroup.
| Left Hemisphere | Right Hemisphere | ||||||
|---|---|---|---|---|---|---|---|
| NeuroQuant® | Inbrain® | P | NeuroQuant® | Inbrain® | P | ||
| Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | ||||
| Cortical gray matter | 215.69 ± 27.21 | 200.09 ± 25.04 | < 0.001 | 217.99 ± 27.25 | 200.11 ± 24.79 | < 0.001 | |
| NL | 238.116 ± 26.13 | 218.64 ± 21.59 | < 0.001 | 241.73 ± 25.82 | 218.05 ± 21.38 | < 0.001 | |
| MCI | 213.79 ± 22.21 | 201.12 ± 20.27 | < 0.001 | 215.78 ± 22.18 | 201.50 ± 20.15 | < 0.001 | |
| AD | 195.51 ± 19.18 | 177.80 ± 19.58 | < 0.001 | 197.04 ± 17.17 | 178.06 ± 19.60 | < 0.001 | |
| Caudate | 2.80 ± 0.70 | 3.28 ± 0.54 | < 0.001 | 2.83 ± 0.70 | 3.29 ± 0.53 | < 0.001 | |
| NL | 2.62 ± 0.49 | 3.31 ± 0.38 | < 0.001 | 2.82 ± 0.55 | 3.38 ± 0.42 | < 0.001 | |
| MCI | 2.84 ± 0.70 | 3.34 ± 0.60 | < 0.001 | 2.87 ± 0.77 | 3.33 ± 0.56 | < 0.001 | |
| AD | 2.90 ± 0.85 | 3.13 ± 0.57 | < 0.001 | 2.73 ± 0.72 | 3.09 ± 0.52 | < 0.001 | |
| Putamen | 5.50 ± 0.79 | 3.90 ± 0.62 | < 0.001 | 5.26 ± 0.72 | 3.99 ± 0.62 | < 0.001 | |
| NL | 5.88 ± 0.56 | 4.31 ± 0.50 | < 0.001 | 5.68 ± 0.62 | 4.46 ± 0.43 | < 0.001 | |
| MCI | 5.55 ± 0.76 | 3.93 ± 0.50 | < 0.001 | 5.25 ± 0.66 | 3.98 ± 0.52 | < 0.001 | |
| AD | 5.01 ± 0.82 | 3.39 ± 0.60 | < 0.001 | 4.83 ± 0.69 | 3.48 ± 0.60 | < 0.001 | |
| Pallidum | 0.50 ± 0.17 | 1.81 ± 0.25 | < 0.001 | 0.47 ± 0.17 | 1.82 ± 0.26 | < 0.001 | |
| NL | 0.66 ± 0.14 | 1.89 ± 0.25 | < 0.001 | 0.62 ± 0.12 | 1.90 ± 0.23 | < 0.001 | |
| MCI | 0.48 ± 0.14 | 1.80 ± 0.24 | < 0.001 | 0.44 ± 0.14 | 1.79 ± 0.25 | < 0.001 | |
| AD | 0.35 ± 0.11 | 1.74 ± 0.24 | < 0.001 | 0.35 ± 0.12 | 1.79 ± 0.29 | < 0.001 | |
| Thalamus | 7.05 ± 0.79 | 6.33 ± 0.75 | < 0.001 | 7.05 ± 0.84 | 6.10 ± 0.76 | < 0.001 | |
| NL | 7.31 ± 0.92 | 6.78 ± 0.75 | < 0.001 | 7.27 ± 0.96 | 6.44 ± 0.74 | < 0.001 | |
| MCI | 7.04 ± 0.69 | 6.26 ± 0.61 | < 0.001 | 7.05 ± 0.78 | 6.05 ± 0.61 | < 0.001 | |
| AD | 6.80 ± 0.75 | 5.98 ± 0.79 | < 0.001 | 6.80 ± 0.79 | 5.81 ± 0.91 | < 0.001 | |
| Amygdala | 1.44 ± 0.28 | 1.20 ± 0.25 | < 0.001 | 1.37 ± 0.26 | 1.39 ± 0.29 | 0.06† | |
| NL | 1.66 ± 0.25 | 1.40 ± 0.20 | < 0.001 | 1.55 ± 0.23 | 1.62 ± 0.24 | < 0.001 | |
| MCI | 1.43 ± 0.25 | 1.20 ± 0.22 | < 0.001 | 1.38 ± 0.22 | 1.39 ± 0.25 | 0.33† | |
| AD | 1.22 ± 0.19 | 0.98 ± 0.19 | < 0.001 | 1.17 ± 0.22 | 1.14 ± 0.22 | 0.14† | |
| Hippocampus | 3.31 ± 0.75 | 3.55 ± 0.58 | < 0.001 | 3.35 ± 0.74 | 3.60 ± 0.62 | < 0.001 | |
| NL | 4.09 ± 0.56 | 4.07 ± 0.47 | 0.65† | 4.10 ± 0.52 | 4.17 ± 0.50 | 0.02 | |
| MCI | 3.28 ± 0.54 | 3.53 ± 0.44 | < 0.001 | 3.31 ± 0.57 | 3.57 ± 0.49 | < 0.001 | |
| AD | 2.55 ± 0.34 | 3.02 ± 0.40 | < 0.001 | 2.61 ± 0.37 | 3.02 ± 0.37 | < 0.001 | |
| Cerebellum | 61.41 ± 6.16 | 61.70 ± 6.23 | 0.04 | 59.70 ± 5.70 | 60.43 ± 6.14 | < 0.001 | |
| NL | 64.67 ± 6.96 | 64.46 ± 6.91 | 0.46† | 62.18 ± 6.31 | 62.88 ± 6.85 | 0.02 | |
| MCI | 60.82 ± 5.70 | 61.13 ± 6.04 | 0.14† | 59.22 ± 5.25 | 60.00 ± 5.73 | < 0.001 | |
| AD | 59.09 ± 4.66 | 59.90 ± 4.85 | 0.003 | 58.00 ± 5.09 | 58.65 ± 5.40 | 0.03 | |
| Cerebral gray matter* | 431.48 ± 62.85 | 400.11 ± 49.62 | < 0.001 | ||||
| NL | 480.04 ± 51.63 | 436.69 ± 42.85 | < 0.001 | ||||
| MCI | 429.72 ± 44.02 | 402.61 ± 40.14 | < 0.001 | ||||
| AD | 383.03 ± 68.14 | 355.86 ± 38.83 | 0.003 | ||||
| Cerebral white matter* | 447.96 ± 54.46 | 438.53 ± 67.79 | 0.008 | ||||
| NL | 466.59 ± 53.23 | 447.59 ± 48.86 | < 0.001 | ||||
| MCI | 450.32 ± 53.97 | 432.90 ± 59.37 | < 0.001 | ||||
| AD | 423.21 ± 48.38 | 440.23 ± 96.04 | 0.12† | ||||
The units are mL. *Cerebral gray matter and white matter mean volume measured in both hemisphere, †Statistically not significant.