Table 2. The Statistical Results at the Image Level (Number of Pictures).
Mitotic Index | Training Cohort (n = 108) | Validation Cohort (n = 20) | Test Cohort (n = 20) | |||
---|---|---|---|---|---|---|
≤ 5/50 HFPs | > 5/50 HFPs | ≤ 5/50 HFPs | > 5/50 HFPs | ≤ 5/50 HFPs | > 5/50 HFPs | |
True | 2044 | 3130 | 331 | 717 | 411 | 910 |
False | 453 | 354 | 104 | 139 | 198 | 152 |
Total | 2497 | 3484 | 435 | 856 | 609 | 1062 |
Accuracy (95% CI), % | 86.5 (0.856–0.874) | 81.2 (0.790–0.833) | 79.1 (0.771–0.810) | |||
Sensitivity (95% CI), % | 89.8 (0.888–0.908) | 83.8 (0.811–0.861) | 85.7 (0.834–0.877) | |||
Specificity (95% CI), % | 81.9 (0.803–0.833) | 76.1 (0.717–0.800) | 67.5 (0.636–0.712) | |||
Positive predictive value (95% CI), % | 87.4 (0.862–0.884) | 87.3 (0.848–0.895) | 82.1 (0.797–0.843) | |||
Negative predictive value (95% CI), % | 85.2 (0.837–0.866) | 70.4 (0.660–0.744) | 73.0 (0.691–0.766) |
CI: confidence interval