Table 3. The Statistical Results at the Patient Level (Number of Patients).
Mitotic Index | Training Cohort (n = 108) | Validation Cohort (n = 20) | Test Cohort (n = 20) | |||
---|---|---|---|---|---|---|
≤ 5/50 HFPs | > 5/50 HFPs | ≤ 5/50 HFPs | > 5/50 HFPs | ≤ 5/50 HFPs | > 5/50 HFPs | |
True | 48 | 50 | 7 | 9 | 7 | 9 |
False | 6 | 4 | 3 | 1 | 3 | 1 |
Total | 54 | 54 | 10 | 10 | 10 | 10 |
Accuracy (95% CI), % | 90.7 (0.852–0.963) | 80.0 (0.608–0.992) | 80.0 (0.608–0.992) | |||
Sensitivity (95% CI), % | 92.6 (0.813–0.976) | 90.0 (0.541–0.995) | 90.0 (0.541–0.995) | |||
Specificity (95% CI), % | 88.9 (0.767–0.954) | 70.0 (0.354–0.919) | 70.0 (0.354–0.919) | |||
Positive predictive value (95% CI), % | 88.9 (0.767–0.954) | 75.0 (0.428–0.933) | 75.0 (0.428–0.933) | |||
Negative predictive value (95% CI), % | 92.3 (0.806–0.975) | 87.5 (0.467–0.993) | 87.5 (0.467–0.993) |