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. 2021 Jan 27;13(1):e12940. doi: 10.7759/cureus.12940

Table 4. Relevant clinical trials studying the effects of regadenoson on reactive airway diseases.

FEV1: Forced expiratory volume 1; COPD: Chronic obstructive pulmonary disease

Authors Design Sample size  Primary outcome Results
Thomas et al. [29] Randomized, double-blinded placebo-controlled crossover trial  49 COPD Patients Decline in FEV1 No difference between both groups
Leaker et al. [30] Randomized, double-blinded placebo-controlled crossover trial 48 Asthma Patients Decline in FEV1 No difference between both groups
Prenner et al. [31] Randomized, double-blind placebo-controlled study 576 Asthma Patients  Decline in FEV1 No difference between both groups 
Prenner et al. [31] Randomized, double-blind placebo-controlled study 467 COPD Patients Decline in FEV1 No difference between both groups