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. 2020 Dec 14;9:e62576. doi: 10.7554/eLife.62576

Figure 36. A number of input neurons specifically target DAN groups of the PAM or PPL1 clusters.

Neurons providing strong input to PAM or PPL1 DANs are shown. Neuropil areas of inputs to these neurons are shown in gray in (A–C) and synapses to DANs are shown color-coded in (A′-C′); synapse numbers are given in parentheses. The threshold for connectivity is 0.5% of the DANs total inputs (Figure 31). (A-A′) Cluster 8 is comprised of 20 neurons of 10 similar cell types which provide input to subtypes of β-lobe PAM DANs in the SLP: PAM10 (β1; blue); PAM09-vd (β1ped; yellow) and all PAM04 subtypes (β2; green). (B-B′) The single neuron in cluster 11 receives inputs in the CA and connects to PPL105 (α′2α2; orange). (C-C′) The seven neurons in cluster 12 (LAL110, CRE068) receive inputs in the LAL and provide the strongest input to PPL103 (γ2α′1; green). Connections contributing less than 0.5% of a neuron’s total dendritic input have been excluded.

Figure 36.

Figure 36—figure supplement 1. Inputs specific to PAM DANs.

Figure 36—figure supplement 1.

Neurons providing strong input to DANs of the PAM cluster are shown. Neuropil areas indicated (gray) and synapses to DANs are color-coded ; synapse numbers are given in parentheses. (A-A′) The seven neurons of cluster 29 fall into seven cell types, receive inputs in the SMP and connect to PAM15-uc (γ5β′2a; orange) and the PAM13-dd (β′1ap; green). (B-B′) The 12 neurons of cluster 7 fall into four cell types, receive inputs in the SMP and SIP and connect strongly to PAM DANs that are restricted to the β′ (blue synapses) and the γ lobes (green synapses): PAM13 (β′1ap), PAM14 (β′1m), PAM02 (β′2a), PAM06 (β′2m), PAM05 (β′2p), PAM03 (β2β′2a) and PAM12-md (γ3), PAM08 (γ4), PAM01 (γ5), PAM(γ5β′2a). (C-C′) Cluster 32 has nine neurons of four cell types that receive some inputs in the CRE. Cluster 32 provides strong input to PAM14 (β′1) subtypes (orange synapses) and is also upstream of the PAM05-vd (β′2p) subtype (blue synapses) and all PAM13 (β′1ap) subtypes (green synapse). The threshold for connectivity is 0.5% of the DANs total inputs (Figure 31).
Figure 36—figure supplement 2. Inputs specific to PPL1 DANs.

Figure 36—figure supplement 2.

Neuropil areas indicated (gray) and synapses to DANs are color-coded ; synapse numbers are given in parentheses. (A-A′) The two neurons (light blue) of cluster 13 receive inputs in the contralateral SMPs and connect to the negative-valence PPL101(γ1pedc; red) DANs. (B-B′) Cluster 15 has five neurons receiving inputs in the SIP and provides strong input to PPL104 (α′3). (C-C′) The seven neurons of cluster 14 receive inputs in the SMP and are strongly connected to the PPL105 (α′2α2). The threshold for connectivity is 0.5% of the DAN’s total inputs (Figure 31).