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. 2021 Feb 19;116(2):248–256. [Article in Portuguese] doi: 10.36660/abc.20190403

Table 2. – Demographic and laboratory information of CC-Dys patients according to death or heart transplantation.

  No events Events p-value
(n=69) (n=28)
Age (y) 49 [42-54] 47.5 [44.5-52] 0.96
Male, n (%) 42 (61%) 16 (57%) 0.73
Creatinine (mg/dL) 1.01 [0.85-1.14] 1.14 [0.87-1.23] 0.06
Ejection fraction (%) 35 [25-40] 20 [20-30] 0.001
NYHA >1 29 20 0.009
Galectin-3 (ng/mL) 14.4 [10.9-19.1] 18.5 [14.7-23.4] 0.005
Low 39 7  
High 30 21  
NT-proBNP (pg/mL) 542 [281-1337] 2643 [1047-4771] <0.001
Low 50 7
High 19 21
Parasite estimate* 1.77 [0.19-4.2] 1.25 [0.16-12.61] 0.08

Median [25th, 75th percentile) by death or heart transplantation as an outcome. CC-Dys: patients with positive T. cruzi serology and CC with left ventricular dysfunction; NT-proBNP: N-terminal pro B-type natriuretic peptide; NYHA: New York Heart Association. Low Galectin-3 = <15.3 ng/mL; Low NT-proBNP = <1278 pg/mL. *Parasite load per 20mL.