Table 3. – Association between galectin-3 and death or heart transplantation in the CC-Dys subgroup using ROC and Cox regression models, both crude and adjusted for age, sex, serum creatinine level, NYHA functional class >I and LVEF, and using Galectin-3 and NT-proBNP as categorical variables.
Crude Model | Adjusted Model | ||||||
---|---|---|---|---|---|---|---|
AUC | Cutoff | Cutoff Level | p | HR (95%CI) | p | HR (95%CI) | |
Galectin-3 (ng/mL) | 0.71 | 15.3 | Low | ||||
High | 0.007 | 3.27 (1.39-7.71) | 0.04 | 2.63 (1.00-6.90) | |||
NT-proBNP (pg/mL) | 0.80 | 1278 | Low | ||||
High | <0.001 | 5.69 (2.41-13.42) | 0.02 | 3.44 (1.21-9.78) |
AUC: area under the curve; CI: confidence interval; HR: hazard ratio; LVEF: left ventricular ejection fraction; NT-proBNP: N-terminal pro B-type natriuretic peptide; NYHA: New York Heart Association; ROC: receiver operating characteristic