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. 2021 Feb 19;116(2):248–256. [Article in Portuguese] doi: 10.36660/abc.20190403

Table 3. – Association between galectin-3 and death or heart transplantation in the CC-Dys subgroup using ROC and Cox regression models, both crude and adjusted for age, sex, serum creatinine level, NYHA functional class >I and LVEF, and using Galectin-3 and NT-proBNP as categorical variables.

        Crude Model Adjusted Model
AUC Cutoff Cutoff Level p HR (95%CI) p HR (95%CI)
Galectin-3 (ng/mL) 0.71 15.3 Low        
    High 0.007 3.27 (1.39-7.71) 0.04 2.63 (1.00-6.90)
NT-proBNP (pg/mL) 0.80 1278 Low        
    High <0.001 5.69 (2.41-13.42) 0.02 3.44 (1.21-9.78)

AUC: area under the curve; CI: confidence interval; HR: hazard ratio; LVEF: left ventricular ejection fraction; NT-proBNP: N-terminal pro B-type natriuretic peptide; NYHA: New York Heart Association; ROC: receiver operating characteristic