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. 2021 Feb 24;47(4):62. doi: 10.3892/ijmm.2021.4895

Figure 6.

Figure 6

Effects of GC on ultrastructural characteristics, W/D weight ratio, Hyp activity and CD40 expression of lung tissue in LPS-injured CD40-cKO mice. (A) Representative transmission electron microscopy observation (magnification, ×17,000) of lung injury in the (a) control group, (b) LPS group, (c) 12 mg/kg GC group, (d) 24 mg/kg GC group and (e) 48 mg/kg GC group. Effects of GC on (B) W/D weight ratio, (C) Hyp activity and (D) CD40 expression. Wild-type mice were used as the control group. Data are presented as the mean ± SD (n=8). ##P<0.01 vs. control. GC, Ginkgolide C; W/D, wet-to-dry; Hyp, hydroxyproline; cKO, conditional knockout; LPS, lipopolysaccharide; NS, not significant.