Table V.
Effects of GC on inflammatory cytokine levels in the cell medium of LPS-injured alveolar epithelial cells of CD40-cKO mice.
| Group | TNF-α (pg/ml) | IL-1β (pg/ml) | IL-6 (pg/ml) |
|---|---|---|---|
| Control | 13.84±2.55 | 30.38±6.04 | 60.02±14.72 |
| LPS | 85.56±9.57a | 709.65±72.75a | 741.05±104.58a |
| GC (1 µM) | 81.91±7.44 | 729.46±59.26 | 655.20±96.86 |
| GC (10 µM) | 82.22±8.90 | 680.37±69.73 | 616.25±88.45 |
| GC (100 µM) | 87.30±10.30 | 725.60±67.53 | 691.05±108.84 |
Data are presented as the mean ± SD (n=8).
a
P<0.01 vs. control. GC, Ginkgolide C; LPS, lipopolysaccharide; cKO, conditional knockout.