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. 2021 Feb 18;47(4):59. doi: 10.3892/ijmm.2021.4892

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Copyright: © Niu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of NPPB on ER stress-associated markers. ER stress markers and ER stress-associated caspase-dependent apoptosis markers ATF6, JNK, CHOP, caspase-12, PERK and p-PERK were measured via western blotting. β-actin was used as an internal control. The results are presented as the mean ± standard deviation (n=3). ^*P<0.05; ^**P<0.01. HLEC, human lens epithelial cell; NPPB, 5-nitro-2-(3-phenylpropylamino) benzoic acid; ER, endoplasmic reticulum; ATF6, activating transcription factor 6; CHOP, C/EBP homologous protein; p-PERK, phosphorylated protein kinase R-like endoplasmic reticulum kinase.