Table 1.
Baseline Patient Features
| Characteristics | Total Population N = 111 | Negative Skin Prick Test N = 51 | Positive Skin Prick Test N = 60 | p |
|---|---|---|---|---|
| Female gender, N (%) | 71 (63.96) | 33 (64.71) | 38 (63.33) | >0.9999 |
| Male gender, N (%) | 40 (36.04) | 18 (35.29) | 22 (36.67) | >0.9999 |
| Age, median values (IQR), years | 56.00 (43.00–65.00) | 57.00 (49.00–67.00) | 51.50 (42.25–62.75) | 0.0729 |
| Duration of asthma, median val. (IQR), years | 18.0 (10.00–30.00) | 14.00 (10.00–21.00) | 24.50 (13.00–31.75) | 0.0008 |
| FEV1, median values (IQR), % predicted | 61.00 (49.75–74.25) | 66.00 (50.00–78.00) | 59.00 (48.00–73.00) | 0.3367 |
| Blood eosinophils, median v. (IQR), cells/μL | 740.0(200.0–1097) | 750.0 (550.0–1100) | 700.0 (452.5–1010) | 0.5987 |
| Blood basophils, median val. (IQR), cells/μL | 44.0 (30.00–86.00) | 40.00 (20.00–65.00) | 46.00 (30.00–90.00) | 0.7328 |
| BMI, median values (IQR), kg/m2 | 26.17 (23.14–28.13) | 25.21 (22.84–27.76) | 27.02 (23.82–28.82) | 0.0846 |
| Smokers, N (%) | 32 (28.83) | 13 (25.49) | 19 (31.67) | 0.5321 |
| Gastro-esophageal reflux disease, N (%) | 55 (49.55) | 24 (47.06) | 31 (51.67) | 0.7045 |
| Nasal polyposis, N (%) | 51 (45.95) | 27 (52.94) | 24 (40.00) | 0.1867 |
| Bronchiectasis, N (%) | 27 (24.32) | 12 (23.53) | 15 (25.00) | >0.9999 |
| Osteoporosis, N (%) | 27 (24.32) | 12 (23.53) | 15 (25.00) | >0.9999 |
| Anxiety, N (%) | 21 (18.92) | 11 (21.57) | 10 (16.67) | 0.6289 |
| Atopic dermatitis, N (%) | 13 (11.71) | 1 (1.96) | 12 (20.00) | 0.0029 |
| Obstructive sleep apnea syndrome, N (%) | 11 (9.91) | 3 (5.88) | 8 (13.33) | 0.2204 |
Note: Bold entries highlight statistically significant differences between patients with negative SPT versus subjects with positive SPT.