. 2021 Feb 22;16:1457–1472. doi: 10.2147/IJN.S294653

Table 11.

Evaluation of Anti-Inflammatory Effect of DIF, DIF-IC-Loaded Nanoemulgel and Diclofenac Diethylamine Emulgels in Carrageenan and Histamine-Induced Paw Edema Model

Carrageenan-Induced Paw Edema Model				Histamine-Induced Paw Edema Model
Time (Hours)	DIF-Loaded Nanoemulgel	Diclofenac Diethylamine Emulgel	DIF-IC-Loaded Nanoemulgel	DIF Nanoemulgel	Diclofenac Diethylamine Emulgel	DIF-IC Nanoemulgel
1	14.30 ± 0.47	16.10 ± 0.30*	27.40 ± 0.42*/*	13.40 ± 0.36	15.70 ± 0.33**	28.10 ± 0.33*/*
2	24.40 ± 0.29	24.90 ± 0.47^ns	40.40 ± 0.25*/*	25.10 ± 0.62	25.00 ± 0.42^ns	40.10 ± 0.39*/*
3	36.40 ± 0.42*	34.60 ± 0.35	59.90 ± 0.36*/*	35.40 ± 0.50	34.60 ± 0.30^ns	60.20 ± 0.31*/*