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. 2021 Feb 22;13:1803–1815. doi: 10.2147/CMAR.S276290

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© 2021 Yu et al.

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Overexpression of HMGB3 abrogates the impacts of LINC00504 knockdown on breast cancer cells. (A) Western blot analysis was performed to detect HMGB3 protein expression in MCF-7 and MDA-MB-231 cells after pcDNA3.1-HMGB3 or pcDNA3.1 transfection. (B–E) si-LINC00504 in parallel with pcDNA3.1-HMGB3 or pcDNA3.1 was transfected into MCF-7 and MDA-MB-231 cells. CCK-8 assay, flow cytometry and Transwell experiments were done to determine the proliferation, apoptosis, migration, and invasion in the different groups, respectively. *P < 0.05 and **P < 0.01.