Figure 2.
Validation of correlations of the CAF score with differentiation status and overall survival (OS). (A–C) Analyses of the CAF scores of the Wu (A), Nurmik (B) and Calon (C) CAF signatures in poorly differentiated thyroid cancer (PDTC)/anaplastic thyroid cancer (ATC) compared with normal thyroid (NT) tissues and papillary thyroid cancer (PTC). (D–F) Analyses of the CAF scores of the Wu (D), Nurmik (E) and Calon (F) CAF signatures in patients with low thyroid differentiation score (TDS) compared with high-TDS patients in PTC. (G–I) The correlation of OS outcomes with the CAF scores of the Wu (G), Nurmik (E) and Calon (F) CAF signatures in PDTC/ATC patients from the GSE76039 cohort. **p<0.01, ***p<0.001.