Table 2.

Frequency of allergic reaction in patients with l-ASP administration by IV, IM routes or IV and IM routes (n = 98).

Administration route	n (%)	Allergic reactions (%)	p-value*
IV	22 (22.4)	10 (62.5)	< 0.001
IM	48 (49)	0
IV and IM	28 (28.6)	6 (37.5)

^*p-value was calculated using Fisher’s exact test.