Table 2.
Distribution of study characteristics in 3,594,181 birth cohort members
| Characteristics | Individuals with OCD (n = 21,859)a | Individuals without OCD (n = 3,572,322) | P-valueb |
|---|---|---|---|
| Any suicide attempt, No. (%) | 2984 (13.65) | 97,037 (2.72) | <0.001 |
| Male | 947 (10.22) | 45,220 (2.46) | <0.001 |
| Female | 2037 (16.18) | 51,817 (2.99) | <0.001 |
| Age at first suicide attempt, mean (SD), years | 23.05 (6.95) | 22.60 (7.59) | 0.001 |
| Male | 24.68 (7.22) | 23.76 (7.82) | <0.001 |
| Female | 22.30 (6.68) | 21.59 (7.23) | <0.001 |
| Death by suicide, No. (%) | 159 (0.73) | 6746 (0.19) | <0.001 |
| Male | 88 (0.95) | 4921 (0.27) | <0.001 |
| Female | 71 (0.56) | 1825 (0.11) | <0.001 |
| Age at death by suicide, mean (SD), years | 29.33 (7.09) | 26.93 (7.43) | <0.001 |
| Male | 29.38 (6.03) | 27.02 (7.23) | 0.002 |
| Female | 29.26 (8.26) | 26.69 (7.94) | 0.01 |
| Psychiatric comorbidities, No. (%) | |||
| Any comorbidities (at least one) | 16,331 (74.71) | 390,734 (10.94) | <0.001 |
| Affective disorders | 10,101 (46.21) | 166,106 (4.65) | <0.001 |
| Anxiety disorders | 11,331 (51.84) | 150,096 (4.20) | <0.001 |
| Substance use disorders | 3465 (15.85) | 130,485 (3.65) | <0.001 |
| Psychotic disorders | 2189 (9.88) | 26,762 (0.75) | <0.001 |
| Personality disorders | 3353 (15.34) | 32,153 (0.90) | <0.001 |
| Other psychiatric disorders | 6416 (29.35) | 128,622 (3.60) | <0.001 |
OCD obsessive−compulsive disorder, SD standard deviation
aKaplan−Meier estimate of expected cumulative incidence of OCD at age 46 (i.e., at the end of follow-up) is 1.23% (95% CI 1.21−1.25%), under the assumption of no competing risks
bP values are estimated by chi-square test and Fisher’s exact test for categorical variables and independent-sample two-tailed t tests for continuous variables