Fig. 1.

Midbrain inflammatory mRNA transcripts in schizophrenia (SCZ, a–g) and in adult mice prenatally exposed to the viral mimetic, poly(I:C) h–l. The scatter plots depict relative mRNA levels by diagnosis (human cohort: SCZ versus control subjects, circles represent women, triangles represent men) and by prenatal treatment group (mouse cohort: poly(I:C) versus vehicle controls, for analysis by sex, see Supplementary Fig. 2). Human cohort: a SERPINA3, b TNFα, c IL6, d IL1β, e IL8, f IL18, and g IL6ST mRNA. Mouse cohort: h SERPINA3, i TNFα, j IL6, k IL18, and l IL1β mRNA. Data are mean ± SEM. *p < 0.05, **p < 0.01, ****p < 0.0001