Table 2.

Correlations (Spearman’s) between immune marker gene expression and measures of antipsychotic drug treatment and duration of illness

Gene of interest	Chlorpromazine equivalent measure	n	p	Correlation coefficient
AIF mRNA	Life time	22	0.428	0.178
	Mean daily	22	0.009	0.546**
	Last dose	27	0.843	0.040
	Illness duration	27	0.402	0.168
CD68 mRNA	Life time	22	0.033	0.456*
	Mean daily	22	0.007	0.556**
	Last dose	28	0.882	0.029
	Illness duration	28	0.343	0.186
TSPO mRNA	Life time	22	0.433	0.176
	Mean daily	22	0.085	0.376&
	Last dose	28	0.745	−0.064
	Illness duration	28	0.319	0.195
GFAP mRNA	Life time	22	0.343	0.212
	Mean daily	22	0.178	0.298
	Last dose	28	0.731	−0.068
	Illness duration	28	0.620	0.098
TNFα mRNA	Life time	21	0.020	0.503*
	Mean daily	21	0.001	0.649**
	Last dose	27	0.388	0.173
	Illness duration	27	0.084	0.339&
SERPINA3 mRNA	Life time	20	0.201	0.299
	Mean daily	20	0.119	0.360
	Last dose	26	0.209	0.255
	Illness duration	26	0.207	0.256
IL1β mRNA	Life time	21	0.175	0.307
	Mean daily	21	0.021	0.499*
	Last dose	27	0.172	0.271
	Illness duration	27	0.680	0.083&
IL6 mRNA	Life time	21	0.010	0.547*
	Mean daily	21	0.003	0.618**
	Last dose	27	0.118	0.308
	Illness duration	27	0.475	0.144
IL8 mRNA	Life time	21	0.088	0.381&
	Mean daily	21	0.278	0.248
	Last dose	27	0.547	0.121
	Illness duration	27	0.108	0.316
IL18 mRNA	Life time	22	0.936	0.018
	Mean daily	22	0.691	0.090
	Last dose	28	0.798	−0.051
	Illness duration	28	0.517	0.128
IL6ST mRNA	Life time	22	0.575	0.127
	Mean daily	22	0.867	0.038
	Last dose	28	0.280	−0.211
	Illness duration	28	0.773	0.057
IL1A	Life time	20	0.120	0.359
	Mean daily	20	0.003	0.634**
	Last dose	26	0.343	0.194
	Illness duration	26	0.585	−0.112
IL17RA	Life time	22	0.026	0.473*
	Mean daily	22	<0.0001	0.702****
	Last dose	28	0.287	0.209
	Illness duration	28	0.907	0.023

^&p < 0.1, *p < 0.05, **p < 0.01, ***p < 0.001, ****p< 0.0001