Table 3.

Cerebrospinal fluid cfDNA derived from lumbar puncture

Case	Age	Sex	Molecular diagnosis	WHO grade	Mib-1index (%)	Primary/ recurrence	Gd enhancement	Cytology class	Radiographical dissemination	Tumor DNA				Final concen tration (ng/μ L)	Match
										IDH	TERT 228	TERT 250	H3 K27M
1	43	F	GBM,IDH mut	IV	22.8	rec	+	1	+	mut	wt	wt	wt	0.06	Yes
2	74	M	GBM,IDH wt	IV	9.5	pri	+	2	−	wt	mut	wt	wt	0.13	Yes
3	53	M	GBM,IDH wt	IV	11.6	pri	+	2	+	wt	mut	wt	wt	0.54	Yes
4	84	F	GBM,IDH wt	IV	58	pri	+	2	+	wt	wt	wt	wt	0.07	−
5	33	M	GBM,IDH wt	IV	60	pri	+	2	−	wt	wt	wt	wt	0.018	−
6	18	F	DMG,H3 K27M	IV	5.4	pri	+	2	−	wt	wt	wt	mut	0.03	Yes
7	47	F	AA,IDH mut	III	50	pri	−	2	−	mut	wt	wt	wt	0.075	Yes
8	43	M	AO,IDH mut	III	22.8	rec	+	3	+	mut	mut	wt	wt	0.06	Yes
9	43	F	AO,IDH mut	III	25	pri	−	2	−	mut	mut	wt	wt	0.04	No
10	49	F	DA,IDH mut	II	1.4	pri	−	na	−	mut	wt	wt	wt	0.02	No
11	63	F	OA IDH mut	II	3.7	pri	−	2	−	mut	mut	wt	wt	0.03	No