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. 2021 Feb 26;11:4737. doi: 10.1038/s41598-021-81714-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Exposure to CSF can affect multiple virulence factors in A. baumannii. (A) Heat map of multiple virulence factor associated genes that were differentially expressed in A. baumannii strain A118. Asterisks represent a P-value of < 0.05. (B) Poly-N-acetylglucosamine (PNAG) assays were conducted with strains A118 in LB or LB supplemented with 4% CSF. (C) Percentage viability of HEK-293 cells under exposure to various concentrations of A. baumannii strains A118 or AB5075 supplemented with or without 4% CSF. (D) Percentage survival of Galleria mellonella when inoculated with A. baumannii strain A118 with or without 4% CSF.