Table 1.
CSF regulated genes in A. baumannii A118.
| Gene ID | Gene name | Log2fold change | p-adj | Gene associated function |
|---|---|---|---|---|
| AbA118F_3259 | bauB | 3.55 | 1.4 E-21 | Iron compound ABC uptake transporter substrate-binding protein |
| AbA118F_1017 | fimA | 3.09 | 1.2 E-160 | Fimbrial protein |
| AbA118F_3260 | bauE | 2.84 | 1.1 E-06 | putative iron compound ABC uptake transporter, ATP-binding protein |
| AbA118F_0516 | 2.81 | 3.4 E-126 | Exporter protein, RND family | |
| AbA118F_0517 | 2.79 | 9.5 E-142 | Polyketide synthase module | |
| AbA118F_0746 | 2.77 | 9.1 E-36 | hypothetical protein | |
| AbA118F_0519 | 2.58 | 2.2 E-94 | Acyl-CoA dehydrogenase | |
| AbA118F_0523 | 2.54 | 1.1 E-63 | Autoinducer synthesis protein SolI | |
| AbA118F_3262 | bauD | 2.52 | 2.9 E-02 | Iron transport protein |
| AbA118F_0514 | 2.50 | 1.2 E-117 | hypothetical protein | |
| AbA118F_0518 | 2.45 | 2.2 E-66 | Acyl carrier protein | |
| AbA118F_0515 | 2.39 | 2.4 E-65 | hypothetical protein | |
| AbA118F_0745 | 2.37 | 1.9 E-12 | Hypothetical protein | |
| AbA118F_2656 | 2.34 | 9.0 E-3 | Urease beta subunit | |
| AbA118F_3134 | fimB | 2.32 | 4.7 E-18 | P pilus assembly protein, chaperone PapD |
| AbA118F_1015 | 2.30 | 1.1 E-124 | outer membrane usher protein precursor | |
| AbA118F_2504 | 2.16 | 1.9 E-102 | Biotin carboxylase of acetyl-CoA carboxylase | |
| AbA118F_0483 | 2.14 | 1.2 E-107 | ATP synthase delta chain | |
| AbA118F_1447 | 2.12 | 6.7 E-08 | hypothetical protein | |
| AbA118F_2933 | rpmC | 2.12 | 4.5 E-85 | LSU ribosomal protein L29p (L35e)-rpmC |
| AbA118F_1014 | 2.10 | 1.5 E-78 | fimbrial adhesin precursor | |
| AbA118F_2505 | 2.09 | 1.4 E-58 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase | |
| AbA118F_3136 | 2.09 | 8.8 E-19 | Fimbrial adhesin | |
| AbA118F_0481 | 2.08 | 7.4 E-108 | ATP synthase gamma chain | |
| AbA118F_2932 | 2.08 | 3.0 E-94 | SSU ribosomal protein S17p (S11e) | |
| AbA118F_0041 | 2.03 | 1.2 E-90 | 33–36 kDa outer membrane protein | |
| AbA118F_2934 | 1.99 | 1.3 E-92 | LSU ribosomal protein L16p (L10e) | |
| AbA118F_3202 | 1.97 | 1.3 E-96 | Translation elongation factor Ts | |
| AbA118F_1819 | 1.97 | 1.3 E-104 | LSU ribosomal protein L10p (P0) | |
| AbA118F_2936 | 1.96 | 1.7 E-92 | LSU ribosomal protein L22p (L17e) | |
| AbA118F_2935 | 1.96 | 2.1 E-93 | SSU ribosomal protein S3p (S3e) | |
| AbA118F_1818 | 1.93 | 5.6 E-95 | LSU ribosomal protein L7p/L12p (P1/P2) | |
| AbA118F_0484 | atpF | 1.92 | 2.7 E-90 | ATP synthase F0 sector subunit b |
| AbA118F_0113 | 1.91 | 7.9 E-58 | hypothetical protein | |
| AbA118F_3133 | 1.91 | 9.3 E-43 | Fimbrial protein precursor | |
| AbA118F_2937 | 1.90 | 1.5 E-88 | SSU ribosomal protein S19p (S15e) | |
| AbA118F_3135 | 1.89 | 3.5 E-08 | type 1 fimbriae anchoring protein FimD | |
| AbA118F_0482 | atpA | 1.88 | 7.0 E-97 | ATP synthase alpha chain |
| AbA118F_2359 | 1.87 | 1.5 E-05 | hypothetical protein | |
| AbA118F_3256 | basD | 1.86 | 2.1 E-08 | Non-ribosomal peptide synthetase modules, siderophore biosynthesis |
| AbA118F_1925 | 1.85 | 4.2 E-55 | Succinyl-CoA ligase [ADP-forming] beta chain | |
| AbA118F_0480 | atpD | 1.83 | 9.1 E-76 | ATP synthase beta chain |
| AbA118F_1016 | 1.80 | 2.1 E-67 | P pilus assembly protein, chaperone PapD | |
| AbA118F_2749 | 1.77 | 1.5 E-08 | Homocysteine S-methyltransferase-like protein | |
| AbA118F_0513 | 1.76 | 4.2 E-11 | 4′-phosphopantetheinyl transferase | |
| AbA118F_3345 | 1.76 | 1.8 E-20 | Hypothetical protein | |
| AbA118F_1919 | 1.76 | 2.5 E-14 | tRNA-Thr | |
| AbA118F_3265 | basB | 1.76 | 3.8 E-08 | Non-ribosomal peptide synthetase |
| AbA118F_2938 | 1.75 | 2.9 E-79 | LSU ribosomal protein L2p (L8e) | |
| AbA118F_2939 | 1.75 | 1.1 E-73 | LSU ribosomal protein L23p (L23Ae) | |
| AbA118F_0485 | 1.73 | 3.2 E-66 | ATP synthase F0 sector subunit c | |
| AbA118F_2311 | 1,72 | 2.3 E-49 | SSU ribosomal protein S18p : SSU ribosomal protein S18p, zinc-independent | |
| AbA118F_0479 | atpC | 1.72 | 3.8 E-64 | ATP synthase epsilon chain |
| AbA118F_3254 | basF/entF | 1.72 | 1.6 E-04 | Isochorismatase of siderophore biosynthesis |
| AbA118F_2312 | 1.71 | 1.7 E-66 | SSU ribosomal protein S6p | |
| AbA118F_1530 | 1.69 | 2.0 E-30 | hypothetical protein | |
| AbA118F_3044 | 1.68 | 5.0 E-62 | 3-oxoacyl-[acyl-carrier protein] reductase | |
| AbA118F_0520 | 1.68 | 3.7 E-41 | Polyketide synthase module | |
| AbA118F_2927 | 1.67 | 6.2 E-71 | SSU ribosomal protein S8p (S15Ae) | |
| AbA118F_3258 | bauA | 1.67 | 1.9 E-11 | Ferrichrome-iron receptor |
| AbA118F_3481 | 1.67 | 3.4 E-14 | Oxidoreductase, short-chain dehydrogenase/reductase family | |
| AbA118F_3201 | 1.66 | 2.9 E-02 | hypothetical protein | |
| AbA118F_1820 | 1.66 | 9.5E-72 | LSU ribosomal protein L1p (L10Ae) | |
| AbA118F_1821 | 1.64 | 2.3 E-69 | LSU ribosomal protein L11p (L12e) | |
| AbA118F_1340 | 1.64 | 1.5 E-30 | Ferrichrome-iron receptor | |
| AbA118F_0638 | tssL | 1,63 | 1.2 E-39 | Putative transmembrane protein |
| AbA118F_2322 | pgaB | 1.63 | 1.5 E-19 | Biofilm PGA synthesis deacetylase PgaB |
| AbA118F_2321 | pgaA | 1.63 | 2.1 E-26 | Biofilm PGA outer membrane secretin PgaA |
| AbA118F_0387 | 1.61 | 1.3 E-54 | Hemolysin | |
| AbA118F_2915 | 1.60 | 2.9 E-53 | LSU ribosomal protein L17p | |
| AbA118F_2024 | 1.59 | 9.3 E-43 | Sodium-alanine symporter family protein | |
| AbA118F_2923 | 1.59 | 4.0 E-42 | LSU ribosomal protein L30p (L7e) | |
| AbA118F_1509 | 1.59 | 1.8 E-63 | Translation elongation factor Tu | |
| AbA118F_0149 | 1.58 | 8.3 E-26 | Imidazolonepropionase | |
| AbA118F_2323 | pgaC | 1.56 | 2.8 E-13 | Biofilm PGA synthesis N-glycosyltransferase PgaC |
| AbA118F_2920 | 1.56 | 6.5 E-44 | LSU ribosomal protein L36p : LSU ribosomal protein L36p, zinc-dependent | |
| AbA118F_1621 | 1.55 | 4.6 E-54 | Glyceraldehyde-3-phosphate dehydrogenase, putative | |
| AbA118F_1623 | 1.55 | 2.0 E-43 | Gluconate transporter family protein | |
| AbA118F_3243 | 1.54 | 3.1 E-52 | hypothetical protein | |
| AbA118F_0791 | 1.54 | 1.0 E-50 | Phosphoglycerate kinase | |
| AbA118F_2940 | 1.53 | 8.5 E-60 | LSU ribosomal protein L4p (L1e) | |
| AbA118F_2921 | 1.53 | 4.0 E-65 | Protein translocase subunit SecY | |
| AbA118F_3255 | entE/basE | 1.52 | 2.5 E-06 | 2,3-dihydroxybenzoate-AMP ligase of siderophore biosynthesis |
| AbA118F_0114 | 1.52 | 5.7 E-29 | hypothetical protein | |
| AbA118F_0148 | 1.51 | 2.6 E-11 | Formiminoglutamase | |
| AbA118F_2924 | 1.51 | 1.3 E-48 | SSU ribosomal protein S5p (S2e) | |
| AbA118F_1954 | 1.50 | 7.5 E-53 | LSU ribosomal protein L21p | |
| AbA118F_3316 | -1.50 | 1.59 E-29 | Phosphate ABC transporter, periplasmic phosphate-binding protein PstS | |
| AbA118F_1136 | -1.52 | 2.8 E-04 | putative zinc-type alcohol dehydrogenase-like protein YbdR | |
| AbA118F_1643 | -1.56 | 5.3 E-04 | Twin-arginine translocation protein TatB | |
| AbA118F_0751 | -1.57 | 1.6 E-04 | TPR-repeat-containing protein | |
| AbA118F_2679 | -1.69 | 1.5 E-02 | hypothetical protein | |
| AbA118F_1644 | -1.82 | 5.8 E-05 | Twin-arginine translocation protein TatC | |
| AbA118F_2820 | -1.86 | 3.9 E-02 | Allantoin racemase | |
| AbA118F_2477 | -1.87 | 4.6 E-10 | Mg(2 +)-transport-ATPase-associated protein MgtC | |
| AbA118F_0711 | -1.89 | 5.4 E-16 | Acyl-CoA dehydrogenase | |
| AbA118F_0704 | -1.99 | 1.4 E-02 | 2-aminoethylphosphonate ABC transporter substrate-binding protein | |
| AbA118F_2199 | -2.06 | 2.4 E-04 | Protein co-occuring with molybdenum cofactor biosynthesis protein B | |
| AbA118F_0907 | -2.14 | 5.2 E-20 | outer membrane porin, putative | |
| AbA118F_2367 | -2.30 | 4.0 E-02 | Phage tail/DNA circulation protein | |
| AbA118F_1645 | -2.39 | 1.2 E-27 | Alkaline phosphatase | |
| AbA118F_1190 | -2.62 | 4.9 E-02 | Lysozyme (N-acetylmuramidase) family | |
| AbA118F_1376 | -2.93 | 3.4 E-02 | Lysozyme (N-acetylmuramidase) family | |
| AbA118F_3137 | -3.07 | 2.8 E-03 | hypothetical protein | |
| AbA118F_2475 | -3.31 | 2.0 E-08 | hypothetical protein | |
| AbA118F_2476 | -3.83 | 2.7 E-11 | Mg(2 +) transport ATPase, P-type |
The table lists all A. baumanii A118 ORFs that are regulated by CSF with a Log2FC ≥|1.5|, p < 0.05.