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Exploratory MR analysis based on GWAS identified SNPs at different significance levels.
| SNPs associated with coffee at different significance levels (N) | Estimate | SE | p |
|---|---|---|---|
| p < 5e–8 (n=5) | −0.128 | 0.196 | 0.516 |
| p < 1e–7 (n=5) | −0.128 | 0.196 | 0.516 |
| p < 1e–6 (n=8) | −0.149 | 0.188 | 0.43 |
| p < 1e–5 (n=22) | −0.169 | 0.159 | 0.288 |
| p < 1e–4 (n=77) | −0.069 | 0.118 | 0.562 |
