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A simple schematic representation of CRISPR system and associated nucleases. The CRISPR/Cas system can be divided into two classes as Class1 and Class2. Class1 CRISPR/Cas system utilize multi-Cas protein complex, whereas Class2 CRISPR/Cas system employ single Cas protein. Furthermore, these two classes are subdivided into six types based on the presence of specific genes. Class1 includes types I, III, and IV, whereas Class2 includes types II, V, and VI
