Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mechanisms by which coupled eNOS regulates the vascular homeostasis and uncoupled eNOS determines hypertension. Increased bioavailability of BH4 and coupled form of eNOS lead to production of NO, by utilizing the l-arginine as a substrate. The NO. further helps to keep the vessel homeostasis and normal blood pressure. Whereas the uncoupled form of eNOS along with increased BH2 levels helps vessel constriction and leads to high blood pressure. Color images are available online.
