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. 2021 Feb 26;4:258. doi: 10.1038/s42003-021-01764-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Principal component analysis and b PLS-DA analysis of untargeted LC-MS metabolomics data of C. elegans fed with control, UV-treated and PFA-treated OP50. c VIP analysis of component 1 of LC-MS metabolomics data of C. elegans fed with control, UV-treated and PFA-treated OP50. d Heatmap of targeted LC-MS metabolomics data of C. elegans fed with control, UV-treated and PFA-treated OP50. e Pathway analysis of metabolites with significant abundance change between worms grown on mock-treated and 0.25% PFA-treated OP50 and f between worms grown on mock-treated and 0.5% PFA-treated OP50. PE_384 = Phosphatidylethanolamine (PE) (38:4) and PE_386 = PE (38:6).