Fig. 5. A high-resolution cis-regulatory atlas of mouse secondary motor cortex (MOs).

a T-SNE visualization of 20 major cell types in MOs identified using SnapATAC. b Fourteen GABAergic subtypes revealed by iterative clustering of 5940 GABAergic neurons (Sst, Pv, and CGE in a). c Gene accessibility score of canonical marker genes for GABAergic subtypes is projected onto the t-SNE embedding. d k-means clustering of 294,304 differentially accessible elements based on chromatin accessibility. e Gene ontology analysis of each cell-type predicted by GREAT analysis²⁷. f Transcription factor motif enriched in each cell group identified using Homer²² (Poisson p-value).