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. 2021 Feb 26;11:4775. doi: 10.1038/s41598-021-84130-y

Figure 5.

Figure 5

Schematic design of the vaccination study. The study consisted of 3 experimental groups of 8 mice each. The first group was vaccinated with recombinant BB0405, the second group was received a tattooed DNA vaccination with BB0405 and the third group received an empty vector DNA vaccination as a control. Mice were vaccinated at t = 0, t = 14 and t = 28 days. They were challenged with infected ticks 2 weeks after the last booster vaccination and sacrificed at day 63.