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. 2021 Feb 25;10(2):39. doi: 10.1167/tvst.10.2.39

Table 2.

Mean Macular Thickness and Volume by Age Group

Age Groups, Tertile (Years)
Tertile 1 69–78 Tertile 2 78–83 Tertile 3 83–101 P Value
Total retina, number of eyes 330 321 255
Macular thickness (µm)
Central circle 278 (33) 277 (28) 277 (42) 0.89
Inner ring 330 (20) 326 (18) 323 (23) 0.001
Outer ring 284 (16) 280 (15) 280 (15) 0.004
Macular volume (mm3)
ETDRS grid 8.3 (0.5) 8.2 (0.4) 8.2 (0.5) 0.002
Inner retinal layers, number of eyes 312 307 236
Macular thickness (µm)
Central circle 190 (28) 188 (23) 187 (26) 0.25
Inner ring 249 (19) 245 (17) 241 (19) <0.0001
Outer ring 206 (15) 203 (14) 201 (14) 0.001
Macular volume (mm3)
ETDRS grid 6.1 (0.4) 6.0 (0.4) 5.9 (0.4) <0.0001
Outer Retinal Layers, number of eyes 330 321 255
Macular thickness (µm)
Central circle 86 (11) 86 (12) 86 (20) 0.40
Inner ring 80 (5) 79 (3) 80 (7) 0.98
Outer ring 77 (3) 77 (2) 78 (3) 0.10
Macular volume (mm3)
ETDRS grid 2.2 (0.1) 2.2 (0.1) 2.2 (0.1) 0.57
Nerve fiber layer, number of eyes 319 309 241
Macular thickness (µm)
Central circle 13 (3) 13 (3) 13 (2) 0.32
Inner ring 23 (3) 24 (3) 24 (3) 0.21
Outer ring 39 (6) 39 (6) 39 (7) 0.83
Macular volume (mm3)
ETDRS grid 1.0 (0.1) 1.0 (0.2) 1.0 (0.2) 0.93
Ganglion cell layer, number of eyes 317 309 240
Macular thickness (µm)
Central circle 17 (13) 16 (4) 16 (4) 0.08
Inner ring 46 (7) 45 (6) 44 (7) <0.0001
Outer ring 30 (4) 30 (4) 29 (4) <0.0001
Macular volume (mm3)
ETDRS grid 0.9 (0.1) 0.9 (0.1) 0.9 (0.1) <0.0001
Inner plexiform layer, number of eyes 307 308 230
Macular thickness (µm)
Central circle 22 (4) 21 (4) 21 (4) 0.04
Inner ring 38 (4) 37 (4) 37 (4) <0.0001
Outer ring 26 (2) 25 (3) 25 (2) 0.006
Macular volume (mm3)
ETDRS grid 0.80 (0.07) 0.78 (0.07) 0.78 (0.07) 0.0004
Inner nuclear layer, number of eyes 307 308 230
Macular thickness (µm)
Central circle 22 (7) 23 (6) 24 (7) 0.10
Inner ring 39 (4) 39 (3) 39 (3) 0.03
Outer ring 30 (3) 30 (2) 30 (2) 0.13
Macular volume (mm3)
ETDRS grid 0.9 (0.1) 0.9 (0.1) 0.9 (0.1) 0.08
Outer plexiform layer, number of eyes 311 311 234
Macular thickness (µm)
Central circle 28 (6) 28 (7) 28 (6) 0.61
Inner ring 34 (4) 34 (5) 34 (4) 0.89
Outer ring 27 (2) 27 (2) 27 (2) 0.16
Macular volume (mm3)
ETDRS grid 0.8 (0.1) 0.8 (0.1) 0.8 (0.1) 0.27
Outer nuclear layer, number of eyes 311 311 234
Macular thickness (µm)
Central circle 90 (12) 90 (12) 87 (15) 0.01
Inner ring 69 (8) 68 (9) 65 (10) 0.0001
Outer ring 54 (6) 53 (7) 52 (6) 0.003
Macular volume (mm3)
ETDRS grid 2 (0.2) 2 (0.2) 2 (0.2) 0.001
Photoreceptor layer, number of eyes 330 321 255
Macular thickness (µm)
Central circle 69 (5) 68 (5) 68 (4) 0.004
Inner ring 64 (2) 64 (2) 64 (2) 0.65
Outer ring 64 (2) 64 (2) 64 (2) 0.34
Macular volume (mm3)
ETDRS grid 1.8 (0.1) 1.8 (0.1) 1.8 (0.1) 0.83
Retinal pigment epithelium, number of eyes 330 321 255
Macular thickness (µm)
Central circle 17 (10) 18 (11) 18 (20) 0.59
Inner ring 15 (5) 15 (3) 15 (6) 0.77
Outer ring 13 (2) 13 (1) 13 (2) 0.08
Macular volume (mm3)
ETDRS grid 0.4 (0.1) 0.4 (0.04) 0.4 (0.1) 0.25

Numbers are presented as mean (SD).