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Laser-engraved crossed line incisions: spatial appearance. a) Macroscopic top view and b) side view of cartilage biopsy with laser-engraved cross-wise line incisions and c) µCT giving a three-dimensional impression of the precise and highly regular grid pattern. d) Calcein-AM staining of ASC seeded on laser-engraved cartilage disc showing a high density of vital cells inside the incisions.
