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. 2021 Jan 30;10(2):199. doi: 10.3390/antiox10020199

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Protective effect of TO extracts and metabolites against UV irradiation (1 h)-induced damage in rat skin slices. (A) Typical electron paramagnetic resonance (EPR) signals of mixtures of DEPMPO-OOH + DEPMPO-OH in the supernatants of post-irradiated skin slices incubated with aqueous DEPMPO (15 mM). SOD, superoxide dismutase (10 U/mL); CAT, catalase (5000 U/mL); NTR, neutral resin subfraction; ●, DEPMPO-OH central lines. (B) Total DEPMPO adducts levels. (C) MDA-TBA levels. Values represent means ± SEM (n = 8). Statistics: * p < 0.05 and ** p < 0.01 vs. TO, ^# p < 0.05 vs. EtTO and ^§ p < 0.01 vs. UV-irradiated untreated slices, by one-way ANOVA (p < 0.01) followed by Newman–Keuls test.