Table 3.

Predicted and experimental values of the optimized SIM niosomal formulation (n = 3).

Solution	CPC Concentration	Type of Surfactant	Conc of Surfactant	Y1	Y2	Y3	Y4	Desirability
Predicted	4	Span 60	5	83.03	211.87	18.82	74.67	0.654
Experimental	4	Span 60	5	80.21	198.62	36.76	68.78	0.654
Bais %	-	-	-	0.03	0.05	0.12	0.08	-

%Bias = (predicted value − experimental value)/experimental value.