Table 1.
Baseline demographic and clinical characteristics.
| Clinical Evaluation (n = 50) |
Endoscopic Evaluation (n = 50) |
Histologic Evaluation (n = 47) |
||||
|---|---|---|---|---|---|---|
| Active (17) | Inactive (33) | Active (27) | Inactive (23) | Active (31) | Inactive (16) | |
| Male/female | 10/7 | 16/17 | 16/11 | 10/13 | 18/13 | 8/8 |
| Age | 52 (22–76) | 51.5 (21–76) | 51.5 (21–65) | 52.5 (28–76) | 52 (21–65) | 51.5 (28–76) |
| Years from diagnosis | 12.5 (1–28) | 13 (1.2–36) | 12.5 (1–33) | 13 (1.2–36) | 13.5 (12–36) | 12.5 (1.2–34) |
| Crohn’s Disease (CD) | 7 (41%) | 19 (58%) | 14 (52%) | 12 (52%) | 15 (48%) | 9 (56%) |
| CD localization | ||||||
| Ileal | 1 (14%) | 9 (47%) | 4 (29%) | 6 (50%) | 5 (33%) | 5 (55%) |
| Colonic | 1 (14%) | 0 (0%) | 1 (7%) | 0 (0%) | 1 (7%) | 0 (%) |
| Ileo-colonic | 5 (72%) | 10 (53%) | 9 (64%) | 6 (50%) | 9 (60%) | 4 (45%) |
| Ulcerative Colitis (UC) | 10 (59%) | 14 (42%) | 13 (48%) | 11 (48%) | 16 (52%) | 7 (44%) |
| UC localization | ||||||
| Proctitis | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Left sided colitis | 7 (70%) | 5 (36%) | 8 (62%) | 4 (36%) | 9 (56%) | 3 (43%) |
| Pancolitis | 3 (30%) | 9 (64%) | 5 (38%) | 7 (64%) | 7 (44%) | 4 (67%) |
| Intestinal surgery | ||||||
| CD | 4 (57%) | 11 (58%) | 7 (50%) | 8 (67%) | 9 (60%) | 5 (56%) |
| UC | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Therapy | ||||||
| Infliximab | 4 (23%) | 12 (36%) | 8 (30%) | 8 (35%) | 9 (29%) | 6 (37%) |
| Adalimumab | 3 (18%) | 7 (21%) | 6 (22%) | 4 (17%) | 6 (19%) | 2 (13%) |
| Vedolizumab | 5 (29%) | 14 (43%) | 8 (30%) | 11 (47%) | 11 (36%) | 8 (50%) |
| Golimumab | 2 (12%) | 0 (0%) | 2 (7%) | 0 (0%) | 2 (6%) | 0 (0%) |
| Ustekinumab | 3 (18%) | 0 (0%) | 3 (11%) | 0 (0%) | 3 (10%) | 0 (0%) |
| Oral supplementation Vitamin D | ||||||
| Yes | 7 (41%) | 17 (52%) | 11 (41%) | 13 (57%) | 14 (45%) | 8 (50%) |
| No | 8 (47%) | 15 (45%) | 14 (52%) | 9 (39%) | 15 (48%) | 7 (44%) |
| n.a. | 2 (12%) | 1 (3%) | 2 (7%) | 1 (4%) | 2 (7%) | 1 (6%) |
| Season of sample collection | ||||||
| Autumn | 4 (24%) | 3 (9%) | 4 (15%) | 3 (14%) | 5 (16%) | 2 (13%) |
| Winter | 6 (35%) | 10 (30%) | 9 (33%) | 7 (30%) | 8 (26%) | 5 (31%) |
| Spring | 3 (17%) | 9 (27%) | 6 (22%) | 6 (26%) | 9 (29%) | 3 (19%) |
| Summer | 4 (24%) | 11 (33%) | 8 (30%) | 7 (30%) | 9 (29%) | 6 (37%) |
n (Median; range); n (%). n.a.: not applicable. CD: Chron’s disease. UC: ulcerative colitis.