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. 2021 Jan 26;10(2):176. doi: 10.3390/antiox10020176

Figure 8.

Figure 8

Effects of indomethacin alone and with oral pre-treatments of famotidine or A. anthelmintica (200, 100 mg/kg) on gastric inducible nitric oxide expression (iNOS) in rats. (A) Gastric mucosa of the control group showing scanty immunoexpression of iNOS within the basal parts of the gastric glands (arrows), (B) gastric mucosa of the ulcer group showing marked expression of iNOS within the degenerated gastric glands (arrows), (C) gastric mucosa of famotidine group showing marked decrease the expression of iNOS within the gastric glands (arrows), (D) gastric mucosa of A. anthelmintica (200 mg/kg) group showing marked decrease in the expression of iNOS within the gastric glands (arrows indicate expression within the basal parts of the glands), (E) gastric mucosa of A. anthelmintica (100 mg/kg) group showing a decrease in the expression of iNOS within the gastric glands (arrows), iNOS antibody, bar = 100 µm. (F) Representative bar graph of the percentage of immunopositive area. Statistical analyses were carried out by one-way ANOVA followed by Tukey’s post hoc test, mean ± SEM. * Significantly different from control group at p < 0.05. @ Significantly different from indomethacin (ulcer) group at p < 0.05. # Significantly different from A. anthelmintica (200 mg/kg) group at p < 0.05.