Table 2.
Interrupted time-series analysis of changes in trends of incidence and mortality rate of multidrug-resistant bloodstream infections.
| Outcomes | Pre-Intervention Trend |
Change in Level a |
Change in Trend b |
Relative Effect c % |
|---|---|---|---|---|
|
Incidence
density |
−0.09 (−0.25 to 0.07) |
−0.11 (−1.00 to 0.77) |
0.10 (−0.06 to 0.26) |
98.9 (−301.4 to 499.2) |
| Early mortality | 0.009 (−0.03 to 0.05) |
0.06 (−0.14 to 0.26) |
−0.01 (−0.05 to 0.03) |
−72.1 (−147.8 to 3.5) |
| Late mortality | 0.01 (−0.06 to 0.08) |
−0.03 (−0.42 to 0.36) |
−0.005 (−0.08 to 0.07) |
−35.55 (−346.9 to 275.8) |
Data are presented as quarterly incidence density and all-cause crude death rate per 1000 occupied bed days with a 95% confidence interval, unless otherwise specified. a Increase or decrease in the first quarter after the start of the antimicrobial stewardship program (ASP) period with respect to the expected value. b Change in slope for the ASP period. c Percentage difference between the expected value according to the pre-intervention trend and the trend nine years after the start of the ASP.