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Linear (A) and log-linear (B) plots of the relationship between the daily dose of CBA needed for each 1 mg/l of the average steady-state plasma concentration of colistin (Css,avg) and creatinine clearance. The regression equation in (B) with the intercept adjusted from 1.667 to 1.825 is the renally based dosing algorithm. Permission obtained from Oxford University Press (Nation et al., 2017).
