| T2DM | Type 2 diabetes mellitus |
| NICE | The National Institute of Care and Excellence |
| RYGB | Roux-en-Y gastric bypass |
| VTA | ventral tegmental area |
| NA | nucleus acumbens |
| ARC | arcuate nucleus |
| AgRP | Agouti-related peptide |
| POMC | proopiomelanocortin |
| CART | Cocaine and amphetamine-regulated transcript |
| MC3/4R | melanocortin 3 and 4 receptors |
| NTS | nucleus of the solitary tract |
| LPN | lateral parabrachial nucleus |
| CCK | cholecystokinin |
| GLP-1 | Glucagon-like peptide-1 |
| PYY | peptide tyrosine tyrosine |
| PP | Pancreatic polypeptide |
| PVN | Paraventricular nucleus of hypothalamus |
| PP | pancreatic polypeptide |
| NPY | Neuropeptide Y |
| OXM | Oxyntomodulin |
| GOAT | Ghrelin O-acyltransferase |
| RCT | Randomised Controlled Trial |
| SNPs | single nucleotide polymorphisms |
| FTO | fat mass and obesity-associated |
| SCFAs | Short-chain fatty acids |
| NDC | non-digestible carbohydrates |
| FFAR2/3 | free fatty acids receptors 2 and 3 |