Table 2.

Associations of PARP-1 total expression with clinicopathological parameters in uveal melanoma patients.

Clinical Factors	PARP-1 Low Expression (0–3)	PARP-1 High Expression (4–12)	p-value
Gender
Male	9	27	0.033
Female	26	29
Age
≤ 63	20	23	0.135
> 63	15	33
Ciliary body involvement
No	24	30	0.156
Yes	11	26
Iris involvement
No	33	51	0.576
Yes	2	5
Irido-corneal angle involvement
No	1	6	0.171
Yes	34	50
Intrascleral extension
No	1	12	0.014
Yes	34	44
Extrascleral extension
No	32	49	0.560
Yes	3	7
Tumor size
≤15 mm	25	30	0.079
>15 mm	10	26
Mitoses
≤4	25	31	0.126
>4	10	23
Grade
G1 + G2	32	40	0.022
G3	3	16
Chromosome 3 loss
No	11	5	0.008
Yes	16	35
Metastases
No	19	28	0.691
Yes	16	28