Table 8.

Chicory extracts in hepatic disorders and their potentially responsible effective compounds.

Extract Type and Plant Part	Type of Study	Results	Responsible Functional Natural Products	References
Dried chicory root	in vivo, in growing swine models	- hepatoprotective action, potential therapeutic action in metabolic disorders	- inulin	[135]
Chicory seeds aqueous extract	in vivo, in diabetes, and oleic acid-induced NAFLD and NASH	- alleviate hyperglycemia, reduce lipidemic content, modulate insulin resistance, alleviate NAFLD and NASH	- caffeic acid, chlorogenic acid, and chicoric acid	[136]
Chicory root fractions	in vivo, in high-fat-induced NAFLD murine models	- alleviate NAFLD via AMP-activated protein kinase	- polysaccharides (sorbin, glucose, fructose, and glucitol)	[137]
Whole chicory plant powder extract	in vivo, in thioacetamide-induced liver cirrhosis in murine models	- reduce oxidative stress, hepatoprotective action	phenolics, chicoric acid, inulin	[138]