. 2021 Jan 28;11(2):98. doi: 10.3390/life11020098

Table 2.

Clinical performance of rCNV-seq for detection of CNVs in 217 amniotic fluid samples.

Primary Indication for Chromosome Testing	Sample (n)	rCNV-Seq Result
Primary Indication for Chromosome Testing	Sample (n)	Abnormal	Normal
Advanced Maternal Age (≥35 Years)	152	4 (T21)	148
Abnormal serum screening result (<35 years)	41	2 (T21 and 47,XXX)	39
Previously given birth to child with a chromosomal disorder	8	1 (T18)	7
Structural abnormality by ultrasound	7	1 (T21)	6
One parent is a carrier of a chromosomal disorder	2	0	2
Advanced maternal age (≥35 years) and secondary indication ^#	7	0	7
Total	217	8	209

^# Secondary indications included abnormal serum screening result, previously given birth to child with a chromosomal disorder, structural abnormality by ultrasound or one parent is a carrier of a chromosomal disorder.