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. 2021 Jan 29;11(2):188. doi: 10.3390/biom11020188

Table 4.

Human F-box lectins, their carbohydrate ligands and protein expression in the organs.

Common Name
(HUGO Name if Different)
Gene Symbol Carbohydrate Preferential Affinity Protein Expression in the Organs
Cyclin F CCNF a) Appendix, bone marrow, lung, lymph node, skin, spleen, tonsil
F-box protein 2 FBXO2 N-acetylglucosamine disaccharide chitobiose [86] Breast, ovary, pancreas
F-box protein 3 FBXO3 a) b)
F-box protein 4 FBXO4 a) b)
F-box protein 5 FBXO5 a) Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, pancreas, proximal digestive tract, skin
F-box protein 6 FBXO6 High-mannose glycoproteins [87] Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, pancreas, proximal digestive tract, skin
F-box protein 7 FBXO7 a) Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, pancreas, proximal digestive tract, skin
F-box protein 8 FBXO8 a) Bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, pancreas, proximal digestive tract, skin
F-box protein 9 FBXO9 a) b)
F-box protein 10 FBXO10 a) Cervix (uterine), colon, duodenum, endometrium, fallopian tube, lung, prostate, rectum, seminal vesicle, small intestine, testis
F-box protein 11 FBXO11 a) b)
F-box protein 15 FBXO15 a) b)
F-box protein 16 FBXO16 a) Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, pancreas, proximal digestive tract, skin
F-box protein 17 FBXO17 Sulfated and galactose-terminated glycoproteins [88] b)
F-box protein, helicase, 18 FBXO18 a) Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, pancreas, proximal digestive tract, skin
LIM domain 7 LMO7 a) b)
F-box protein 21 FBXO21 a) Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, proximal digestive tract, skin
F-box protein 22 FBXO22 a) b)
Tetraspanin 17 TSPAN17 a) b)
F-box protein 24 FBXO24 a) b)
F-box protein 25 FBXO25 a) b)
F-box protein 27 FBXO27 a) Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, proximal digestive tract, skin
F-box protein 28 FBXO28 a) b)
F-box protein 30 FBXO30 a) b)
F-box protein 31 FBXO31 a) Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, proximal digestive tract, skin
F-box protein 32 FBXO32 a) b)
F-box protein 33 FBXO33 a) Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, pancreas, proximal digestive tract, skin
F-box protein 34 FBXO34 a) Adrenal gland, bronchus, colon, epididymis, endometrium, gallbladder, placenta, seminal vesicle, skeletal muscle, skin, stomach, testis, thyroid gland
F-box protein 36 FBXO36 a) b)
F-box protein 38 FBXO38 a) b)
F-box protein 39 FBXO39 a) b)
F-box protein 40 FBXO40 a) b)
F-box protein 41 FBXO41 a) b)
F-box protein 42 FBXO42 a) Bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, pancreas
F-box protein 43 FBXO43 a) b)
F-box protein 44 FBXO44 a) Adipose and soft tissue, bone marrow and lymphoid tissues, brain, endocrine tissues, female tissues, gastrointestinal tract, kidney and urinary bladder, lung, male tissues, muscle tissues, pancreas, proximal digestive tract, skin
F-box protein 45 FBXO45 a) b)
F-box protein 46 FBXO46 a) b)
F-box protein 47 FBXO47 a) b)
F-box protein 48 FBXO48 a) Esophagus, kidney, oral mucosa, parathyroid gland, skin, stomach

a) Carbohydrate moieties recognized by this protein have not been discovered yet. b) Only RNA expression data available in The Human Protein Atlas [16,17] and GeneCards [18] databases.