Table 2.
Antibacterial activities of glycopeptides as influenced by the N-Ac-d-Ala-d-Ala dipeptide ligand (disk diffusion method) and relative potency against the Enterococcus faecalis 9 strain.
| N-Ac-d-Ala-d-Ala (μg/mL) | 0 | 10 | 100 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Glycopeptide Concentration (μg/mL) | 5 | 10 | 20 | 5 | 10 | 20 | 5 | 10 | 20 |
| Vancomycin | diffusion zones (mm) | ||||||||
| 14.5 | 16.3 | 18.1 | 11.6 | 13 | 14.5 | 8 | 10.2 | 12 | |
| relative potency | |||||||||
| - | −25% | −25% | −25% | −80% | −60% | −20% | |||
| Eremomycin | diffusion zones (mm) | ||||||||
| 15.8 | 17.6 | 19.5 | 17.7 | 19.4 | 21.5 | 18.2 | 21.1 | 21.5 | |
| relative potency | |||||||||
| - | +12% | +10% | +10% | +15% | +20% | +10% | |||