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Tacrolimus solubility with 20%, 30% and 40% (w/v) of HPβCD in Balanced Salt Solution (BSS®) and Liquifilm® vehicles. Statistical analysis: two-way ANOVA followed by Tukey´s multiple comparison test (* α < 0.05 compared with 20% (w/v) and 30% (w/v) HPβCD in all vehicles); one-way ANOVA followed by Tukey´s multiple comparison test (** α < 0.05 compared with the other two vehicles (MilliQ® water and BSS®).
