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The modified Hryniuk model. 5-FU could be divided into sRDIfb and sRDIfc. The effect of the administration was not considered, which means that only the dose (mg) was used for calculations. RDI, relative dose intensity; ox, oxaliplatin; ir, irinotecan; fb, 5-FU bolus; fc, 5-FU continuous intravenous (Figure modified from reference 12).
