Table 2.
Treatment-related grade 3 or 4 adverse events.
| Men (N = 54) | Women (N = 43) | Total (N = 97) | p | |
|---|---|---|---|---|
| Hematologic | ||||
| Neutropenia | 17 (31.5) | 20 (46.5) | 37 (38.1) | 0.192 |
| Febrile neutropenia | 6 (11.1) | 9 (20.9) | 15 (15.5) | 0.296 |
| Anemia | 0 (0.0) | 1 (2.3) | 1 (1.0) | 0.909 |
| Thrombocytopenia | 1 (1.9) | 4 (9.3) | 5 (5.2) | 0.235 |
| Non-hematologic | ||||
| Anorexia | 1 (1.9) | 1 (2.3) | 2 (2.1) | >0.99 |
| Nausea | 12 (22.2) | 8 (18.6) | 20 (20.6) | 0.853 |
| Vomiting | 6 (11.1) | 3 (7.0) | 9 (9.3) | 0.730 |
| Diarrhea | 4 (7.4) | 2 (4.7) | 6 (6.2) | 0.892 |
| Fatigue | 0 (0.0) | 2 (4.7) | 2 (2.1) | 0.378 |
| Sensory neuropathy | 7 (13.0) | 3 (7.0) | 10 (10.3) | 0.531 |