Table 1.

Nanoparticles (NPs) functionalized with lectin targeting aberrant cancer-associated glycans. Abbreviations: Jacalin of Artocarpus integrifolia (JCA); Ulex europaeus Agglutinin-1 (UEA1); Cratylia mollis seeds lectin (Cramoll); Aleuria aurantia lectin (ALL); Ricinus communis agglutinin (RCA); Lotus tetragonolobus lectin (LTL); 5-fluorouracil (5-FU); (−)-epigallocatechin-3-gallate (EGCG); quantum dots (QDs); polyethylene glycol (PEG); gold nanoparticles (AuNPs).

Lectin	Target	Cancer Type	Nanoparticles	Application	Reference
ConA	TF antigen	Bone cancer	DOX-loaded MSNs	Targeting Therapy	[43]
WGA	Neu5Ac GlcNac	Colon adenocarcinoma	5-FU-EGCG -gelatin-chitosan NPs	Targeting Therapy	[44]
UEA I	α-L-fucose	Colorectal cancer	Fluorescent MSNs	Targeting Diagnosis	[45]
ConA	TF antigen	Adenocarcinoma of the cervix	DOX-loaded graphene QDs -Fe3O4	Targeting Therapy Diagnosis	[46]
JCA	TF antigen	Colorectal and breast adenocarcinoma	Phthalocyanine- PEG-AuNPs	Targeting Therapy	[47]
ConA; RCA; WGA	TF antigen; β-D-galactose; Neu5Ac and GlcNac	Colorectal cancer	Fe2O3 -AuNPs	Targeting Diagnosis	[48]
Cramoll	glucose/mannose	Fibroadenoma and invasive ductal carcinoma human breast tissue	QDs	Targeting Diagnosis	[49]
ALL	LeX	Colon cancer	ATTO 430LS dye-loaded MSNs	Targeting Diagnosis Therapy	[50]
LTL	α-1,2-linked fucose	Prostate carcinoma and melanoma	DOX-loaded liposomes	Targeting Therapy	[51]