Figure 12.

Cell viability studies performed on SG-Sr-ICOS-Fc (white bars) and SD-Sr-ICOS-Fc (black bars) samples with MC3T3-E1 cell line at different exposure times (a) 2 d, (b) 4 d, and (c) 7 d considering different particle concentrations. ** p < 0.01 vs. untreated cells (CTR) (Dunnett’ s test). The graphs show cell viability (%) as mean and standard error obtained from three independent experiments. Cell viability was calculated with the following formula: cell viability = absorbance of sample/absorbance of control (untreated cells) × 100.