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. 2021 Jan 28;10(2):251. doi: 10.3390/cells10020251

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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MiR-210-5p leads to hypertrophic change and cellular aerobic respiration alteration in chondrocytes. (A) The expression of miR-210-5p in chondrocytes after transfection (n = 3 patients). NC, negative control; INC, inhibitor negative control. (B–H) Real-time PCR of gene expression in chondrocytes after transfection (n = 3). (I–L) Seahorse mitochondrial stress and phenotype analysis of ACCs transfected by miR-210-5p mimics and inhibitor (n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.