Table 3.
Effects of phycocyanin on growth of non-tumorigenic cell lines and primary cells.
| Cell Origin | Cell Type | Phycocyanin Concentration | Appl. Time (h) |
Prolif. (%) | IC50 | Morphology | Ref. | ||
|---|---|---|---|---|---|---|---|---|---|
| Ovary (Chin. Hamster) | CHO | 20 | µM | 6 | ≈ | - | - | epithelial | [58] |
| Mammary gland | MCF-10A | 25 | µg/mL | 24 | ↑ | >20 | - | epithelial | [65] |
| Skin | HSF | 1000 | µg/mL | 24 | ≈ | - | - | fibroblast | [62] |
| Skin | CCD-986sk | 40 | µM | 72 | +42 | - | - | fibroblast | [35] |
| Skin | Hs68 | 100 | µM | 72 | ≈ | - | - | fibroblast | [49] |
| Liver | LO2 | 100 | µM | 72 | ≈ | - | - | [55] | |
| Liver | QSG-7701 | 100 | µM | 72 | ≈ | - | - | epithelial | [55] |
| Human heart ventricle | AC-16 | 100 | µM | 72 | ≈ | - | - | [55] | |
| Kidney cortex | HK-2 | 100 | µM | 72 | ≈ | - | - | epithelial | [55] |
| Peripheral blood | NK-82 | 100 | µM | 72 | ≈ | - | - | NK cells | [55] |
| Endothelium of umbilical vein | HUVEC | 100 | µM | 72 | ≈ | - | - | epithelial | [55] |
| Endothelium of umbilical vein | HUVEC | 50 | µg/mL | 80 | +31 | - | - | epithelial | [111] |
| Connective tissue (Mouse) | L929 | 596 | µg/mL | 24 | −25 | 596 | µg/mL | fibroblast | [57] |
-: not given, ↑: increase, ≈: approximately equal/unchanged.