Table 3.

Top-10 epistatic interactions associated with AD.

Order	SNP1	P1	SNP2	P2	P	SVM
1	rs17021105	1.52934 × 10−7	rs8083566	3.48624 × 10−5	1.30237 × 10−9	0.720265781
2	rs7003370	1.93263 × 10−6	rs264173	0.00032777	2.73286 × 10−8	0.694629014
3	rs2832810	6.48301 × 10−5	rs7285350	0.040037803	2.91614 × 10−8	0.694518272
4	rs852549	0.001864809	rs7358822	0.000190734	2.06066 × 10−7	0.706256921
5	rs2010668	0.00234868	rs7358822	0.000190734	2.77707 × 10−7	0.706256921
6	rs2832727	0.000632929	rs7285350	0.040037803	3.38987 × 10−7	0.701605759
7	rs8083566	3.48624 × 10−5	rs723259	0.01579838	3.40313 × 10−7	0.73654485
8	rs10853690	3.48624 × 10−5	rs723259	0.01579838	3.40313 × 10−7	0.73654485
9	rs42733	0.025710022	rs7358822	0.000190734	5.87876 × 10−7	0.706256921
10	rs2832841	5.07116 × 10−5	rs5933762	0.000330143	7.53923 × 10−7	0.727131783

Note: In the table, P1 is the p-value of the Chi-square test on SNP1, P2 is the p-value of the Chi-square test on SNP2, and P is the p-value of the Chi-square test on this 2-SNP combination.