Acronym	Denotation
AP	Adaptor protein
AP-4	Adaptor protein-4
AP-5	Adaptor protein-5
AD	Alzheimer’s disease
APP	amyloid precursor protein
ALR	autophagic lysosome reformation
ATG9	autophagy-related protein 9
AR-HSP-TCC	autosomal-recessive hereditary spastic paraplegia with thinning of the corpus callosum
CI-M6PR	cation-independent mannose-6-phosphate receptor
CSMN	cortico-spinal motor neurons
HSPs	Hereditary Spastic Paraplegias
LAMP1	Lysosome associated Membrane Protein1
LOF	Loss of function
MRI	Magnetic Resonance Imaging
PtdIns3P/PI3P	phosphatidylinositol 3-phosphate
PSEN2	presenilin 2
TCC	thin corpus callosum
FYVE domain	Fab1, YOTB, Vac1, and EEA1 domain